The microcal peaqitc has a wide affinity range and offers excellent reproducibility. Laboratory equipment malvern microcal itc200 user manual. They are portable and developed to meet the needs of instrumentation engineers and quality managers, both in laboratory and in field work. This kit will ship with at least 90 days of use before material expiry.
Using a 32bit microprocessor and a fast ad conversation technology, the microcal 2000 achieves advanced flexibility and high performance with two insulated channels. Microcal itc 200 system getting started booklet man055901en 00. Microcal itc 200 operating instructions 28963977 aa 7 introduction 1 regulatory information 1. It delivers direct, labelfree, in solution measurement of all binding and thermodynamic parameters in a single experiment. Microcal is a subsidiary of ge healthcare biosciences corporation and it is a world leader in the development of advanced calorimetry systems. L, seven times greater than both the semiautomated microcal itc200 and fully automated autoitc200 models.
This booklet provides guidance through the basic steps in a microcal itc 200 experiment using reagents supplied in the microcal itc 200 test kit. These products typically do not have pictures or detailed descriptions. All efforts have been made to make the origin software as accurate and free of bugs as possible. Isothermal titration calorimtery microcal autoitc200. Semiautomated maintenance minimizes operator intervention and the system is upgradable to the fully automated microcal autoitc200, making it ideal for laboratories where speed, sensitivity and the ability to accommodate higher workloads in the future are paramount. Microcal t100, ee460015 insert, extraction tool, instruction manual and report of calibration. Microcal itc200 system user manual center for macromolecular. Microcal offers several different itc instruments, including the vp itc and itc200. The fisher scientific encompass program offers items which are not part of our distribution portfolio. Inventor for 1stcommercial microcal dsc and itc almost 0 publish papers 2009 acquired by ge in 2008 8 ge history of microcal instruments mc1 mc2 omega mcs vpdsc vpitc capdsc auto itc i itc200 auto itc200 ppc 1975 1985 1995 2005 1977 1985 1987 1992 1996 1998 2001 2000 2004 2007 2008. Reference material test kit vp cap,peaq dsc manual and auto.
Direct and labelfree measurement in solution, of binding affinity, stoichiometry, enthalpy and entropy. Microcal itc200 getting started handbook microcal itc200 user manual. Microcal itc200 system integrated structural biology. The microcal itc200 is a highly sensitive, low volume isothermal titration calorimeter for the labelfree in solution study of biomolecular interactions. Experiment and method files microcal peaqitc control software can open calorimetry data files experiment. The technique measures small changes in heat capacity in a fixed volume of solution under constant temperature and pressure. Page 46 for more information, see microcal peaqitc user manual. Microcal autoitc200 system from ge healthcare life. Follow the onscreen instructions and click finish when the installation is complete.
Microcal peaqitc from malvern panalytical selectscience. Please familiarize yourself with the microcal autoitc200 users manual abbreviated as the manual in the following texts before starting your experiments. Refer to the microcal itc200 getting started guide and user manual for more information perform waterinwater titrations at the end of the day to check the system. Mau120030 rev b vpdsc microcalorimeter users manual. To reinstall a titration syringe on microcal auto itc200 after monthly maintenance, follow these simple steps. Understanding biomolecular interactions using microcal itc.
Microcal itc 200 system getting started is designed to introduce you to the basic operations of microcal itc 200 system and software1. User manual for the microcal auto itc200 instrument. Measurement selectable thermocouple type k, t, j, r, s, n and e. The microcal 3 thermocouple simulator helps ensure that the frequent checking of thermometer accuracies is a routine operation.
Microcal auto itc200 installing a titration syringe. Overview and technical specifications information on itc technology and microcals products please click here for individual platformresource costings. Microcal itc200 calciumedta tutorial brown university. The thermometer calibrator designed to simulate a chosen temperature, allowing standard k, j or t thermocouple thermometers to be tested or recalibrated simply and quickly, without the need for additional specialised equipment or conversion tables. A note is used to indicate information that is important for troublefree and optimal use of the product. Accurate and reliable eurotron 365 days a year microcal. Ge microcal itc200 manuals manuals and user guides for ge microcal itc200. Microcal autoitc200 isothermal titration calorimeter from malvern. Isothermal titration calorimeter introduction to itc200. Expect material for single use, triplicate testing.
We have 1 ge microcal itc200 manual available for free pdf download. New and used calorimetry systems, bomb calorimeters, chemical reactors, pressure vessels to buy and sell. View and download ge microcal itc200 operating instructions manual online. Microcal itc200 adalah kalorimeter isothermal titration bervolume rendah yang sangat sensitif untuk studi interaksi biomolekul dalam larutan. General how to use this manual this manual describes the itc200 operation, software and maintenance. Microcal autoitc200 user manual english malvern panalytical. A tip contains useful information that can improve or optimize your procedures. Microcal itc200 cleaning the titration syringe youtube. Microcal auto itc200 replacing the pipette youtube. Mau120030 rev b microcal, llc 22 industrial drive east northampton, ma 01060 usa phone. Removing the syringe, cleaning it manually along with careful inspection for any damage, should therefore be performed monthly as a part of a. Microcal itc200 system getting started booklet 28991191 ab 5 introduction introduction microcal itc 200 system getting started is designed to introduce you to the basic operations of microcal itc200 system and software 1. Cold junction compensation cjc selectable onoff, autooff selectable onoff and selectable display contrast adjustment.
Calorimeters for sale new and used lab calorimeters. Typographical conventions software texts and commands are identified by bold italic text. Microcal microcalorimeters are used in a wide range of applications from basic research to the discovery and development of small molecule drugs, biotherapeutics and vaccines. Scientific plotting software to analyze calorimetric data from the microcal mc2, mcs or vpdsc differential scanning. Microcal peaqitc for high sensitivity measurement of all. Microcalorimeters, malvern panalytical microcal range dksh. Alat ini memberikan pengukuran langsung dari semua parameter yang mengikat dalam percobaan tunggal dan dapat menganalisis kelemahan terhadap pengikat afinitas tinggi, dengan menggunakan sampel sekitar 10. The pipette, which holds the titration syringe on microcal autoitc200, does normally not need to be removed from the system. Microcal auto itc200 cleaning the titration syringe youtube. Microcal itc200 calcium edta tutorial january 16, 20 1 jennifer arruda getting started. Double click on vpitc and this will open origin to the rawitc window.
Microcal itc200 operating instructions 28963977 aa. The microcal itc200 is located on the 2nd floor of lhrrb, in the cmi bay. Before you start, book time on the ppms calendar 2. Microcal itc200 isothermal titration calorimeter from. Login to the computer using your ppms credentials ecommons id and password 3. Code model table b power supply 8172 2 4 1 typical ordering code 8172 8174 microcal t500, instruction manual and report of calibration. Expect material for least 5 runs with 6 duplicates from this kit. Inventor for 1stcommercial microcal dsc and itc almost 0 publish papers 2009 acquired by ge in 2008 8 ge history of microcal instruments mc1 mc2 omega mcs vpdsc vpitc capdsc auto itc i itc200 auto itc200 ppc 1975 1985 1995 2005 1977 1985. Microcal 3 temperature simulator eti thermometer shop.
Microcal auto itc200 system is designed to address the needs of todays life science researchers particularly those engaged in drug discovery. Syringe and cell cleaning functions are semi automated and. Selectable thermocouple type k, t, j, r, s, n and e. Microcal itc200 system getting started english man0559. Excellence in measurements microcal t100 t200 fluid. User manual for the microcal autoitc200 instrument. The power switch is at the back of the unit on the right hand. The calibrator is designed to simulate a chosen temperature to test thermocouple type k, j, t, r, n, s and e thermometers without the need for specialised equipment or conversion tables.
A spinning syringe is utilized for injecting and mixing of reactants. Ge microcal itc200 operating instructions manual 64 pages. Microcal itc200 laboratory equipment pdf manual download. Washing module 28 pages laboratory equipment malvern microcal itc200 operating instructions manual 86 pages. The manual microcal vp itc, while providing excellent signal to noise, has a large sample cell volume of 1400. Ability to source power to the uut, or use external power supply. Microcal itc200 for isothermal titration calorimetry.
The system can be upgraded to the fully automated microcal autoitc200, which is suitable for use in laboratories. The microcal 1 plus thermocouple simulator and thermometer helps ensure that the frequent checking of thermometer accuracies is a routine operation. It delivers direct measurement of all binding parameters in a single experiment and can analyze weak to high affinity binders, using as little as 10 g sample. Such changes occur when chemical bonds are formed or broken, such as those which occur during small molecule binding to a. The data can be easily and rapidly generated with minimal sample preparation and system optimization. Ge microcal itc200 operating instructions manual pdf. Instructions for using the kit are given in this booklet. The system combines the performance of microcal itc200, a highly sensitive isothermal titration calorimeter with full automation for a complete solution when unattended operation is desired. The microcal autoitc200 is a fully automated cleaning steps, titrations, filling cells, equilibrations, etc. Cjc selectable onoff, autooff selectable onoff and selectable display contrast adjustment.
Its broad affinity range helps analysis of weak to high affinity binders with a very good repeatability. Ge microcal itc200 operating instructions manual pdf download. The high throughput screening resource center has a ge microcal autoitc200 for performing automated isothermal titration calorimetry. These portable, easytouse temperature calibrators are designed to simulate a chosen temperature, allowing you to check type k, j or t thermocouple thermometers capabilities vary depending on model selected and ensure they are working accurately to. This booklet provides guidance through the basic steps in a microcal itc200 experiment using reagents supplied in the microcal itc200 test kit. High resolution pressure control capable of precise generation and pressure control in the micro inch of water column pressure ranges.
The microcal vpitc isothermal titration calorimeter unit directly measures heat evolved or absorbed in liquid samples as a result of mixing precise amounts of reactants. Section 1 contains general descriptions of the system, its parts and tools, the software, how to perform a. Microcal vpitc operating instructions 28963979 aa 7 introduction 1 regulatory information 1. Project status the full amount of the requested funds. The microcal itc200 is developed for convenience and very high sensitivity. This kit allows users to test instrument performance using edta. Malvern microcal microcalorimeters enable characterization of biomolecular interactions in solution user manual for the microcal autoitc200. Microcal autoitc200 system from ge healthcare selectscience. Microcal itc200 system user manual integrated structural.
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